Reduction of IFN-I responses by plasmacytoid dendritic cells in a longitudinal trans men cohort

Type I interferons (IFN-I) are important mediators of antiviral immunity and autoimmune diseases. Female plasmacytoid dendritic cells (pDCs) exert an elevated capacity to produce IFN-I upon toll-like receptor 7 (TLR7) activation compared to male pDCs, and both sex hormones and X-encoded genes have b...

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Detalles Bibliográficos
Autores principales: Grünhagel, Benjamin, Borggrewe, Malte, Hagen, Sven Hendrik, Ziegler, Susanne M., Henseling, Florian, Glau, Laura, Thiele, Rebecca-Jo, Pujantell, Maria, Sivayoganathan, Varshi, Padoan, Benedetta, Claussen, Janna M., Düsedau, Arne, Hennesen, Jana, Bunders, Madeleine J., Bonn, Stefan, Tolosa, Eva, Krebs, Christian F., Dorn, Christoph, Altfeld, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637924/
https://www.ncbi.nlm.nih.gov/pubmed/37953956
http://dx.doi.org/10.1016/j.isci.2023.108209

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