Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review

Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%–8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent a...

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Autores principales: Chen, Jinyan, He, Dong, Guo, Gengyin, Zhang, Keke, Sheng, Wenliang, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637930/
https://www.ncbi.nlm.nih.gov/pubmed/37954329
http://dx.doi.org/10.1016/j.heliyon.2023.e21204
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author Chen, Jinyan
He, Dong
Guo, Gengyin
Zhang, Keke
Sheng, Wenliang
Zhang, Zhen
author_facet Chen, Jinyan
He, Dong
Guo, Gengyin
Zhang, Keke
Sheng, Wenliang
Zhang, Zhen
author_sort Chen, Jinyan
collection PubMed
description Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%–8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent aggressive gross total resection and postoperative radiotherapy, experienced recurrence and subsequently underwent a second operation. To better understand the disease and explore treatment options, we briefly report this case and review the relevant literature.
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spelling pubmed-106379302023-11-11 Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review Chen, Jinyan He, Dong Guo, Gengyin Zhang, Keke Sheng, Wenliang Zhang, Zhen Heliyon Case Report Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%–8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent aggressive gross total resection and postoperative radiotherapy, experienced recurrence and subsequently underwent a second operation. To better understand the disease and explore treatment options, we briefly report this case and review the relevant literature. Elsevier 2023-10-22 /pmc/articles/PMC10637930/ /pubmed/37954329 http://dx.doi.org/10.1016/j.heliyon.2023.e21204 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Chen, Jinyan
He, Dong
Guo, Gengyin
Zhang, Keke
Sheng, Wenliang
Zhang, Zhen
Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_full Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_fullStr Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_full_unstemmed Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_short Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_sort pediatric gliosarcoma, a rare central nervous system tumor in children: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637930/
https://www.ncbi.nlm.nih.gov/pubmed/37954329
http://dx.doi.org/10.1016/j.heliyon.2023.e21204
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