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Uncovering the mechanism of Qidan Dihuang Granule in the treatment of diabetic kidney disease combined network pharmacology, UHPLC-MS/MS with experimental validation

BACKGROUND AND AIM: Diabetic Kidney Disease (DKD) is a common microvascular complication of diabetes mellitus. Multi-center, randomized controlled trials have shown that Qidan Dihuang Granule (QDDHG) reduces the levels of albuminuria of DKD. However, the specific mechanisms of QDDHG on DKD are not c...

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Detalles Bibliográficos
Autores principales: Xiang, Lei, Cai, Xiangsheng, Zhao, Xiaoshan, Liu, Yuanling, Xiao, Ya, Jiang, Pingping, Yin, Lianghong, Song, Dan, Jiang, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638057/
https://www.ncbi.nlm.nih.gov/pubmed/37954274
http://dx.doi.org/10.1016/j.heliyon.2023.e21714