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Visualization of conformational transition of GRP94 in solution
GRP94, an ER paralog of the heat-shock protein 90 family, binds and hydrolyses ATP to chaperone the folding and maturation of its selected clients. Compared with other hsp90 proteins, the in-solution conformational dynamics of GRP94 along the ATP hydrolysis cycle are less understood, hindering our u...
Autores principales: | Sun, Shangwu, Zhu, Rui, Zhu, Mengyao, Wang, Qi, Li, Na, Yang, Bei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638095/ https://www.ncbi.nlm.nih.gov/pubmed/37949474 http://dx.doi.org/10.26508/lsa.202302051 |
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