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Visualization of conformational transition of GRP94 in solution

GRP94, an ER paralog of the heat-shock protein 90 family, binds and hydrolyses ATP to chaperone the folding and maturation of its selected clients. Compared with other hsp90 proteins, the in-solution conformational dynamics of GRP94 along the ATP hydrolysis cycle are less understood, hindering our u...

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Detalles Bibliográficos
Autores principales: Sun, Shangwu, Zhu, Rui, Zhu, Mengyao, Wang, Qi, Li, Na, Yang, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638095/
https://www.ncbi.nlm.nih.gov/pubmed/37949474
http://dx.doi.org/10.26508/lsa.202302051

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