Optimal molecular binding data and pharmacokinetic profiles of novel potential triple-action inhibitors of chymase, spleen tyrosine kinase, and prostaglandin D2 receptor in the treatment of asthma

BACKGROUND: Asthma is a chronic and complex pulmonary condition that affects the airways. A total of 250,000 asthma-related deaths are recorded annually and several proteins including chymase, spleen tyrosine kinase, and prostaglandin D2 receptor have been implicated in the pathophysiology of asthma...

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Detalles Bibliográficos
Autores principales: Akinnusi, Precious Ayorinde, Olubode, Samuel Olawale, Adebesin, Ayomide Oluwadarasimi, Alade, Adebowale Abiodun, Nwoke, Victor Chinedu, Shodehinde, Sidiqat Adamson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638233/
https://www.ncbi.nlm.nih.gov/pubmed/37947895
http://dx.doi.org/10.1186/s43141-023-00577-8

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