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A chromosome-level genome assembly of Korean mint (Agastache rugosa)

Agastache rugosa, also known as Korean mint, is a perennial plant from the Lamiaceae family that is traditionally used for various ailments and contains antioxidant and antibacterial phenolic compounds. Molecular breeding of A. rugosa can enhance secondary metabolite production and improve agricultu...

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Autores principales: Park, Hyun-Seung, Jo, Ick Hyun, Raveendar, Sebastin, Kim, Nam-Hoon, Gil, Jinsu, Shim, Donghwan, Kim, Changsoo, Yu, Ju-Kyung, So, Yoon-Sup, Chung, Jong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638305/
https://www.ncbi.nlm.nih.gov/pubmed/37949898
http://dx.doi.org/10.1038/s41597-023-02714-x
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author Park, Hyun-Seung
Jo, Ick Hyun
Raveendar, Sebastin
Kim, Nam-Hoon
Gil, Jinsu
Shim, Donghwan
Kim, Changsoo
Yu, Ju-Kyung
So, Yoon-Sup
Chung, Jong-Wook
author_facet Park, Hyun-Seung
Jo, Ick Hyun
Raveendar, Sebastin
Kim, Nam-Hoon
Gil, Jinsu
Shim, Donghwan
Kim, Changsoo
Yu, Ju-Kyung
So, Yoon-Sup
Chung, Jong-Wook
author_sort Park, Hyun-Seung
collection PubMed
description Agastache rugosa, also known as Korean mint, is a perennial plant from the Lamiaceae family that is traditionally used for various ailments and contains antioxidant and antibacterial phenolic compounds. Molecular breeding of A. rugosa can enhance secondary metabolite production and improve agricultural traits, but progress in this field has been delayed due to the lack of chromosome-scale genome information. Herein, we constructed a chromosome-level reference genome using Nanopore sequencing and Hi-C technology, resulting in a final genome assembly with a scaffold N50 of 52.15 Mbp and a total size of 410.67 Mbp. Nine pseudochromosomes accounted for 89.1% of the predicted genome. The BUSCO analysis indicated a high level of completeness in the assembly. Repeat annotation revealed 561,061 repeat elements, accounting for 61.65% of the genome, with Copia and Gypsy long terminal repeats being the most abundant. A total of 26,430 protein-coding genes were predicted, with an average length of 1,184 bp. The availability of this chromosome-scale genome will advance our understanding of A. rugosa’s genetic makeup and its potential applications in various industries.
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spelling pubmed-106383052023-11-11 A chromosome-level genome assembly of Korean mint (Agastache rugosa) Park, Hyun-Seung Jo, Ick Hyun Raveendar, Sebastin Kim, Nam-Hoon Gil, Jinsu Shim, Donghwan Kim, Changsoo Yu, Ju-Kyung So, Yoon-Sup Chung, Jong-Wook Sci Data Data Descriptor Agastache rugosa, also known as Korean mint, is a perennial plant from the Lamiaceae family that is traditionally used for various ailments and contains antioxidant and antibacterial phenolic compounds. Molecular breeding of A. rugosa can enhance secondary metabolite production and improve agricultural traits, but progress in this field has been delayed due to the lack of chromosome-scale genome information. Herein, we constructed a chromosome-level reference genome using Nanopore sequencing and Hi-C technology, resulting in a final genome assembly with a scaffold N50 of 52.15 Mbp and a total size of 410.67 Mbp. Nine pseudochromosomes accounted for 89.1% of the predicted genome. The BUSCO analysis indicated a high level of completeness in the assembly. Repeat annotation revealed 561,061 repeat elements, accounting for 61.65% of the genome, with Copia and Gypsy long terminal repeats being the most abundant. A total of 26,430 protein-coding genes were predicted, with an average length of 1,184 bp. The availability of this chromosome-scale genome will advance our understanding of A. rugosa’s genetic makeup and its potential applications in various industries. Nature Publishing Group UK 2023-11-10 /pmc/articles/PMC10638305/ /pubmed/37949898 http://dx.doi.org/10.1038/s41597-023-02714-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Park, Hyun-Seung
Jo, Ick Hyun
Raveendar, Sebastin
Kim, Nam-Hoon
Gil, Jinsu
Shim, Donghwan
Kim, Changsoo
Yu, Ju-Kyung
So, Yoon-Sup
Chung, Jong-Wook
A chromosome-level genome assembly of Korean mint (Agastache rugosa)
title A chromosome-level genome assembly of Korean mint (Agastache rugosa)
title_full A chromosome-level genome assembly of Korean mint (Agastache rugosa)
title_fullStr A chromosome-level genome assembly of Korean mint (Agastache rugosa)
title_full_unstemmed A chromosome-level genome assembly of Korean mint (Agastache rugosa)
title_short A chromosome-level genome assembly of Korean mint (Agastache rugosa)
title_sort chromosome-level genome assembly of korean mint (agastache rugosa)
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638305/
https://www.ncbi.nlm.nih.gov/pubmed/37949898
http://dx.doi.org/10.1038/s41597-023-02714-x
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