Transcriptomic analysis reveals that RasGEF1b deletion alters basal and LPS-induced expression of genes involved in chemotaxis and cytokine responses in macrophages

Ras guanine nucleotide exchange factor member 1b (RasGEF1b) of the RasGEF/CDC25 domain-containing family is preferentially expressed by macrophages. However, information is lacking about its role in macrophage function. In this study, we generated mice with ubiquitous deletion of Rasgef1b and used R...

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Detalles Bibliográficos
Autores principales: Fernandes, Heliana B., de Oliveira, Isadora Mafra, Postler, Thomas S., Lima, Sérgio Q., Santos, Cícera A. C., Oliveira, Michaelle S., Leão, Felipe B., Ghosh, Sankar, Souza, Maria C., Andrade, Warrison, Silva, Aristóbolo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638313/
https://www.ncbi.nlm.nih.gov/pubmed/37950057
http://dx.doi.org/10.1038/s41598-023-47040-9

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