tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig

Intrauterine growth restriction (IUGR) impairs neonatal weight and causes multiple organ dysplasia. IUGR not only threatens human health but is also a significant constraint to the development of animal husbandry. However, the molecular mechanism underlying IUGR remains to be further elucidated. tRN...

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Autores principales: Jianfeng, Ma, Mailin, Gan, Yitang, Yang, Lei, Chen, Ye, Zhao, Lili, Niu, Yan, Wang, Shunhua, Zhang, Jingyong, Wang, Li, Zhu, Linyuan, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638418/
https://www.ncbi.nlm.nih.gov/pubmed/37949905
http://dx.doi.org/10.1038/s41597-023-02715-w
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author Jianfeng, Ma
Mailin, Gan
Yitang, Yang
Lei, Chen
Ye, Zhao
Lili, Niu
Yan, Wang
Shunhua, Zhang
Jingyong, Wang
Li, Zhu
Linyuan, Shen
author_facet Jianfeng, Ma
Mailin, Gan
Yitang, Yang
Lei, Chen
Ye, Zhao
Lili, Niu
Yan, Wang
Shunhua, Zhang
Jingyong, Wang
Li, Zhu
Linyuan, Shen
author_sort Jianfeng, Ma
collection PubMed
description Intrauterine growth restriction (IUGR) impairs neonatal weight and causes multiple organ dysplasia. IUGR not only threatens human health but is also a significant constraint to the development of animal husbandry. However, the molecular mechanism underlying IUGR remains to be further elucidated. tRNA-derived small RNA (tsRNAs) is a regulative non-coding RNA, which has recently been reported to correlate with the onset and progression of several diseases. In this study, we investigated the tsRNAs expression profiles of IUGR pigs. A tsRNAs dataset for multiple organs in normal and IUGR pigs was generated, including muscle, liver, spleen and intestine. We further analyzed the characteristics of tsRNAs in different organs of pigs, and KEGG pathway analysis was performed to investigate possible pathways involved. This dataset will provide valuable information for further exploring the molecular mechanism of IUGR formation.
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spelling pubmed-106384182023-11-11 tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig Jianfeng, Ma Mailin, Gan Yitang, Yang Lei, Chen Ye, Zhao Lili, Niu Yan, Wang Shunhua, Zhang Jingyong, Wang Li, Zhu Linyuan, Shen Sci Data Data Descriptor Intrauterine growth restriction (IUGR) impairs neonatal weight and causes multiple organ dysplasia. IUGR not only threatens human health but is also a significant constraint to the development of animal husbandry. However, the molecular mechanism underlying IUGR remains to be further elucidated. tRNA-derived small RNA (tsRNAs) is a regulative non-coding RNA, which has recently been reported to correlate with the onset and progression of several diseases. In this study, we investigated the tsRNAs expression profiles of IUGR pigs. A tsRNAs dataset for multiple organs in normal and IUGR pigs was generated, including muscle, liver, spleen and intestine. We further analyzed the characteristics of tsRNAs in different organs of pigs, and KEGG pathway analysis was performed to investigate possible pathways involved. This dataset will provide valuable information for further exploring the molecular mechanism of IUGR formation. Nature Publishing Group UK 2023-11-10 /pmc/articles/PMC10638418/ /pubmed/37949905 http://dx.doi.org/10.1038/s41597-023-02715-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Jianfeng, Ma
Mailin, Gan
Yitang, Yang
Lei, Chen
Ye, Zhao
Lili, Niu
Yan, Wang
Shunhua, Zhang
Jingyong, Wang
Li, Zhu
Linyuan, Shen
tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig
title tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig
title_full tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig
title_fullStr tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig
title_full_unstemmed tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig
title_short tRNA-derived small RNA dataset in multiple organs of intrauterine growth-restricted pig
title_sort trna-derived small rna dataset in multiple organs of intrauterine growth-restricted pig
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638418/
https://www.ncbi.nlm.nih.gov/pubmed/37949905
http://dx.doi.org/10.1038/s41597-023-02715-w
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