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Biodistribution and function of coupled polymer-DNA origami nanostructures

Spatial control over the distribution of therapeutics is a highly desired feature, which could limit the side effects of many drugs. Here we describe a nanoscale agent, fabricated from a coupled polymer-DNA origami hybrid that exhibits stability in serum and slow diffusion through tissues, in a mann...

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Detalles Bibliográficos
Autores principales: Joseph, Noah, Shapiro, Anastasia, Gillis, Ella, Barkey, Shirin, Abu-Horowitz, Almogit, Bachelet, Ido, Mizrahi, Boaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638432/
https://www.ncbi.nlm.nih.gov/pubmed/37949918
http://dx.doi.org/10.1038/s41598-023-46351-1