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Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus

Systemic lupus erythematosus (SLE) is a chronic, multisystemic autoimmune disease that is diagnosed using specific clinical and biochemical inclusion criteria. Here, we report the case of a young adult who was initially diagnosed with dysphagia and later diagnosed with SLE. Other rheumatological and...

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Autores principales: Hegazy, Asmaa, Aleidan, Fahad, AlShammari, Saitah, Alhindi, Raghad, Bashir, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638454/
https://www.ncbi.nlm.nih.gov/pubmed/37954800
http://dx.doi.org/10.7759/cureus.46874
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author Hegazy, Asmaa
Aleidan, Fahad
AlShammari, Saitah
Alhindi, Raghad
Bashir, Shahid
author_facet Hegazy, Asmaa
Aleidan, Fahad
AlShammari, Saitah
Alhindi, Raghad
Bashir, Shahid
author_sort Hegazy, Asmaa
collection PubMed
description Systemic lupus erythematosus (SLE) is a chronic, multisystemic autoimmune disease that is diagnosed using specific clinical and biochemical inclusion criteria. Here, we report the case of a young adult who was initially diagnosed with dysphagia and later diagnosed with SLE. Other rheumatological and non-rheumatological conditions were ruled out, and serology revealed that SLE was the cause of the patient’s symptoms. To the best of our knowledge, no previous case studies or prior research identify dysphagia as a presenting symptom of SLE. While esophageal dysmotility ranging from ineffective esophageal motility (IEM) to achalasia can manifest as a later clinical consequence of SLE, it is rarely the first symptom of the disease. After diagnosis, the patient was treated with hydroxychloroquine and prednisolone, which led to significant improvement.
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spelling pubmed-106384542023-11-11 Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus Hegazy, Asmaa Aleidan, Fahad AlShammari, Saitah Alhindi, Raghad Bashir, Shahid Cureus Internal Medicine Systemic lupus erythematosus (SLE) is a chronic, multisystemic autoimmune disease that is diagnosed using specific clinical and biochemical inclusion criteria. Here, we report the case of a young adult who was initially diagnosed with dysphagia and later diagnosed with SLE. Other rheumatological and non-rheumatological conditions were ruled out, and serology revealed that SLE was the cause of the patient’s symptoms. To the best of our knowledge, no previous case studies or prior research identify dysphagia as a presenting symptom of SLE. While esophageal dysmotility ranging from ineffective esophageal motility (IEM) to achalasia can manifest as a later clinical consequence of SLE, it is rarely the first symptom of the disease. After diagnosis, the patient was treated with hydroxychloroquine and prednisolone, which led to significant improvement. Cureus 2023-10-11 /pmc/articles/PMC10638454/ /pubmed/37954800 http://dx.doi.org/10.7759/cureus.46874 Text en Copyright © 2023, Hegazy et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Hegazy, Asmaa
Aleidan, Fahad
AlShammari, Saitah
Alhindi, Raghad
Bashir, Shahid
Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus
title Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus
title_full Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus
title_fullStr Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus
title_full_unstemmed Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus
title_short Esophageal Dysmotility Disorder and Dysphagia as Initial Manifestations of Lupus
title_sort esophageal dysmotility disorder and dysphagia as initial manifestations of lupus
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638454/
https://www.ncbi.nlm.nih.gov/pubmed/37954800
http://dx.doi.org/10.7759/cureus.46874
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