Targeting Kindlin-2 in adipocytes increases bone mass through inhibiting FAS/PPARγ/FABP4 signaling in mice

Osteoporosis (OP) is a systemic skeletal disease that primarily affects the elderly population, which greatly increases the risk of fractures. Here we report that Kindlin-2 expression in adipose tissue increases during aging and high-fat diet fed and is accompanied by decreased bone mass. Kindlin-2...

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Detalles Bibliográficos
Autores principales: Tang, Wanze, Ding, Zhen, Gao, Huanqing, Yan, Qinnan, Liu, Jingping, Han, Yingying, Hou, Xiaoting, Liu, Zhengwei, Chen, Litong, Yang, Dazhi, Ma, Guixing, Cao, Huiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638509/
https://www.ncbi.nlm.nih.gov/pubmed/37969743
http://dx.doi.org/10.1016/j.apsb.2023.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638509/
https://www.ncbi.nlm.nih.gov/pubmed/37969743
http://dx.doi.org/10.1016/j.apsb.2023.07.001

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