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Optimal trial design selection: a comparative analysis between two-arm and three-arm trials incorporating network meta-analysis for evaluating a new treatment

BACKGROUND: Planning the design of a new trial comparing two treatments already in a network of trials with an a-priori plan to estimate the effect size using a network meta-analysis increases power or reduces the sample size requirements. However, when the comparison of interest is between a treatm...

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Detalles Bibliográficos
Autores principales: Ye, Fangshu, Wang, Chong, O’Connor, Annette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638718/
https://www.ncbi.nlm.nih.gov/pubmed/37951877
http://dx.doi.org/10.1186/s12874-023-02089-y