Investigating the role of platelets and platelet-derived transforming growth factor-β in idiopathic pulmonary fibrosis

Transforming growth factor-β1 (TGFβ1) is the key profibrotic cytokine in idiopathic pulmonary fibrosis (IPF), but the primary source of this cytokine in this disease is unknown. Platelets have abundant stores of TGFβ1, although the role of these cells in IPF is ill-defined. In this study, we investi...

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Detalles Bibliográficos
Autores principales: Chong, Deborah L. W., Mikolasch, Theresia A., Sahota, Jagdeep, Rebeyrol, Carine, Garthwaite, Helen S., Booth, Helen L., Heightman, Melissa, Denneny, Emma K., José, Ricardo J., Khawaja, Akif A., Duckworth, Anna, Labelle, Myriam, Scotton, Chris J., Porter, Joanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639018/
https://www.ncbi.nlm.nih.gov/pubmed/37643008
http://dx.doi.org/10.1152/ajplung.00227.2022

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