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A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM
Single-particle cryo-electron microscopy (cryo-EM) can reveal the structures of large and often dynamic molecules, but smaller biomolecules (≤50 kDa) remain challenging targets due to their intrinsic low signal to noise ratio. Methods to help resolve small proteins have been applied but development...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639074/ https://www.ncbi.nlm.nih.gov/pubmed/37791881 http://dx.doi.org/10.1093/nar/gkad784 |