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A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM

Single-particle cryo-electron microscopy (cryo-EM) can reveal the structures of large and often dynamic molecules, but smaller biomolecules (≤50 kDa) remain challenging targets due to their intrinsic low signal to noise ratio. Methods to help resolve small proteins have been applied but development...

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Detalles Bibliográficos
Autores principales: Langeberg, Conner J, Kieft, Jeffrey S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639074/
https://www.ncbi.nlm.nih.gov/pubmed/37791881
http://dx.doi.org/10.1093/nar/gkad784

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