Cargando…

Hypoxia stabilizes SETDB1 to maintain genome stability

Von Hippel–Lindau (VHL) is a tumor suppressor that functions as the substrate recognition subunit of the CRL2(VHL) E3 complex. While substrates of VHL have been identified, its tumor suppressive role remains to be fully understood. For further determination of VHL substrates, we analyzed the physica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Sungryul, Cho, Jin Hwa, Kim, Jong-Hwan, Park, Mijin, Park, Seulki, Kim, Seon-Young, Kim, Seon-Kyu, Kim, Kidae, Park, Sung Goo, Park, Byoung Chul, Moon, Jeong Hee, Lee, Gaseul, Kim, Sunhong, Kim, Jung-Ae, Kim, Jeong-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639076/ https://www.ncbi.nlm.nih.gov/pubmed/37850636 http://dx.doi.org/10.1093/nar/gkad796

Ejemplares similares

Long-term depletion of cereblon induces mitochondrial dysfunction in cancer cells
por: Park, Seulki, et al.
Publicado: (2021)

Serine 389 phosphorylation of 3-phosphoinositide-dependent kinase 1 by UNC-51-like kinase 1 affects its ability to regulate Akt and p70 S6kinase
por: Kim, Kidae, et al.
Publicado: (2020)

The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNA-Induced Silencing of NF-κB–Inducing Kinase
por: Jang, Hanbit, et al.
Publicado: (2020)

Synergistic effect of two E2 ubiquitin conjugating enzymes in SCF(hFBH1) catalyzed polyubiquitination
por: Kim, Jeong-Hoon, et al.
Publicado: (2015)

Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera
por: Kim, Kidae, et al.
Publicado: (2019)

The Short-Chain Fatty Acid Receptor GPR43 Modulates YAP/TAZ via RhoA
por: Park, Bi-Oh, et al.
Publicado: (2021)

Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in EZH2 Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma
por: Park, Sungryul, et al.
Publicado: (2020)

Phosphorylation of REPS1 at Ser709 by RSK attenuates the recycling of transferrin receptor
por: Kim, Seong Heon, et al.
Publicado: (2021)

Downregulation of SETD5 Suppresses the Tumorigenicity of Hepatocellular Carcinoma Cells
por: Park, Mijin, et al.
Publicado: (2022)

Corrigendum to: Downregulation of SETD5 Suppresses the Tumorigenicity of Hepatocellular Carcinoma Cells
por: Park, Mijin, et al.
Publicado: (2022)

Aryl Sulfonamides Induce Degradation of Aryl Hydrocarbon Receptor Nuclear Translocator through CRL4(DCAF15) E3 Ligase
por: Kim, Sung Ah, et al.
Publicado: (2020)

SETDB1 regulates SMAD7 expression for breast cancer metastasis
por: Ryu, Tae Young, et al.
Publicado: (2019)

ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
por: Lee, Jung-Hee, et al.
Publicado: (2017)

USP7 deubiquitinates and stabilizes EZH2 in prostate cancer cells
por: Lee, Jae Eun, et al.
Publicado: (2020)

Novel GPR43 Agonists Exert an Anti-Inflammatory Effect in a Colitis Model
por: Park, Bi-Oh, et al.
Publicado: (2022)

Author Correction: ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
por: Lee, Jung-Hee, et al.
Publicado: (2018)

Histone H4 is cleaved by granzyme A during staurosporine-induced cell death in B-lymphoid Raji cells
por: Lee, Phil Young, et al.
Publicado: (2016)

KDM3A regulates Slug expression to promote the invasion of MCF7 breast cancer cells in hypoxia
por: Ahn, Hyun-Jung, et al.
Publicado: (2020)

GENT2: an updated gene expression database for normal and tumor tissues
por: Park, Seung-Jin, et al.
Publicado: (2019)

Current Knowledge on the Function of α-Methyl Acyl-CoA Racemase in Human Diseases
por: Kong, Gyeyeong, et al.
Publicado: (2020)

Corrigendum: Current Knowledge on the Function of α-Methyl Acyl-CoA Racemase in Human Diseases
por: Kong, Gyeyeong, et al.
Publicado: (2021)

Lipiodol nanoemulsions stabilized with polyglycerol-polycaprolactone block copolymers for theranostic applications
por: Le Kim, Trang Huyen, et al.
Publicado: (2017)

Extracellular Citrate Treatment Induces HIF1α Degradation and Inhibits the Growth of Low-Glycolytic Hepatocellular Carcinoma under Hypoxia
por: Kim, Seon Yoo, et al.
Publicado: (2022)

HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization
por: Choi, Jin Sun, et al.
Publicado: (2014)

Perspectives on the therapeutic potential of short-chain fatty acid receptors
por: Kim, Sunhong, et al.
Publicado: (2014)

Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF–DDX19B interaction
por: Park, Yeonkyoung, et al.
Publicado: (2021)

NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development
por: Kim, Chang-Hyun, et al.
Publicado: (2021)

Molecular Dynamics Studies on the Structural Characteristics for the Stability Prediction of SARS-CoV-2
por: Choi, Kwang-Eun, et al.
Publicado: (2021)

BaSDAS: a web-based pooled CRISPR-Cas9 knockout screening data analysis system
por: Park, Young-Kyu, et al.
Publicado: (2020)

Cutaneous Metastatic Undifferentiated Pleomorphic Sarcoma from a Mediastinal Sarcoma
por: Jeong, Do Seon, et al.
Publicado: (2015)

Effect of immersion into solutions at various pH on the color stability of composite resins with different shades
por: Moon, Ji-Deok, et al.
Publicado: (2015)

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis
por: Nam, S Y, et al.
Publicado: (2011)

PIG3 Regulates p53 Stability by Suppressing Its MDM2-Mediated Ubiquitination
por: Jin, Min, et al.
Publicado: (2017)

Efficacy of a Horticultural Therapy Program Designed for Emotional Stability and Career Exploration among Adolescents in Juvenile Detention Centers
por: Park, Kyoung-Hee, et al.
Publicado: (2022)

2′–5′ oligoadenylate synthetase‑like 1 (OASL1) protects against atherosclerosis by maintaining endothelial nitric oxide synthase mRNA stability
por: Kim, Tae Kyeong, et al.
Publicado: (2022)

Garden-Based Integrated Intervention for Improving Children’s Eating Behavior for Vegetables
por: Kim, Seon-Ok, et al.
Publicado: (2020)

Synthesis of silver nanoparticles embedded with single-walled carbon nanotubes for printable elastic electrodes and sensors with high stability
por: Lee, Jae-Won, et al.
Publicado: (2021)

Oxidation–Responsive Emulsions Stabilized with Poly(Vinyl Pyrrolidone-co-allyl Phenyl Sulfide)
por: Park, Seok Ho, et al.
Publicado: (2020)

Quasi-solid-state highly stretchable circular knitted MnO(2)@CNT supercapacitor
por: Park, Taegyu, et al.
Publicado: (2020)

Long-Term Stability and Integrity of Plasmid-Based DNA Data Storage
por: Nguyen, Hoang Hiep, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_93j1luqjcopuahafiugol9h8db