Leptin favors imbalance of antigen-specific CD4(+) T-cells associated with severity of cat allergy

INTRODUCTION: Obesity can complicate IgE-mediated allergic diseases. In the present study, we aimed to investigate the ability of obesity-related concentrations of leptin to modulate the in vitro effector and regulatory Fel d1-specific CD4(+) T-cell subsets in patients allergic to cat, considered th...

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Detalles Bibliográficos
Autores principales: Vollmer, Carolina, Dias, Aleida, Sales, Marisa, Sacramento, Priscila M., Silva, Júlio Cesar, Oyamada, Hugo A. A., Linhares, Ulisses C., Gupta, Sudhir, Kasahara, Taissa M., Bento, Cleonice A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639137/
https://www.ncbi.nlm.nih.gov/pubmed/37954580
http://dx.doi.org/10.3389/fimmu.2023.1290740

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