PPARδ dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment

BACKGROUND: Peroxisome proliferator-activated receptor delta (PPARδ) promotes inflammation and carcinogenesis in many organs, but the underlying mechanisms remains elusive. In stomachs, PPARδ significantly increases chemokine Ccl20 expression in gastric epithelial cells while inducing gastric adenoc...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Wei, Daoyan, Deguchi, Yasunori, Xu, Weiguo, Tian, Rui, Liu, Fuyao, Xu, Min, Mao, Fei, Li, Donghui, Chen, Weidong, Valentin, Lovie Ann, Deguchi, Eriko, Yao, James C., Shureiqi, Imad, Zuo, Xiangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640489/
https://www.ncbi.nlm.nih.gov/pubmed/37572185
http://dx.doi.org/10.1007/s10120-023-01418-w

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