Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen

Seasonal influenza vaccines must be updated annually and suboptimally protect against strains mismatched to the selected vaccine strains. We previously developed a subunit vaccine antigen consisting of a stabilized trimeric influenza A group 1 hemagglutinin (H1) stem protein that elicits broadly neu...

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Detalles Bibliográficos
Autores principales: Swart, Maarten, Kuipers, Harmjan, Milder, Fin, Jongeneelen, Mandy, Ritschel, Tina, Tolboom, Jeroen, Muchene, Leacky, van der Lubbe, Joan, Izquierdo Gil, Ana, Veldman, Daniel, Huizingh, Jeroen, Verspuij, Johan, Schmit-Tillemans, Sonja, Blokland, Sven, de Man, Martijn, Roozendaal, Ramon, Fox, Christopher B., Schuitemaker, Hanneke, Capelle, Martinus, Langedijk, Johannes P. M., Zahn, Roland, Brandenburg, Boerries
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640631/
https://www.ncbi.nlm.nih.gov/pubmed/37952003
http://dx.doi.org/10.1038/s41541-023-00772-1

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