FKBP5 activates mitophagy by ablating PPAR-γ to shape a benign remyelination environment

Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of the central nervous system (CNS) that is characterized by myelin damage, followed by axonal and ultimately neuronal loss, which has been found to be associated with mitophagy. The etiology and pathology of MS remain elusive. H...

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Detalles Bibliográficos
Autores principales: Sun, Xingzong, Qian, Menghan, Li, Hongliang, Wang, Lei, Zhao, Yunjie, Yin, Min, Dai, Lili, Bao, Hongkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640650/
https://www.ncbi.nlm.nih.gov/pubmed/37952053
http://dx.doi.org/10.1038/s41419-023-06260-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640650/
https://www.ncbi.nlm.nih.gov/pubmed/37952053
http://dx.doi.org/10.1038/s41419-023-06260-7

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