Cargando…

Prevalence of BRCA1 and BRCA2 germline variants in an unselected pancreatic cancer patient cohort in Pakistan

BACKGROUND: BRCA1 and BRCA2 (BRCA1/2) are the most frequently investigated genes among Caucasian pancreatic cancer patients, whereas limited reports are available among Asians. We aimed to investigate the prevalence of BRCA1/2 germline variants in Pakistani pancreatic cancer patients. METHODS: One h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Muhammad, Noor, Azeem, Ayesha, Arif, Shumaila, Naeemi, Humaira, Masood, Iqra, Hassan, Usman, Ijaz, Bushra, Hanif, Faisal, Syed, Aamir Ali, Yusuf, Muhammed Aasim, Rashid, Muhammad Usman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640758/ https://www.ncbi.nlm.nih.gov/pubmed/37951914 http://dx.doi.org/10.1186/s13053-023-00269-x

Ejemplares similares

Prevalence and spectrum of MLH1, MSH2, and MSH6 pathogenic germline variants in Pakistani colorectal cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2019)

Spectrum and prevalence of BRCA1/2 germline mutations in Pakistani breast cancer patients: results from a large comprehensive study
por: Rashid, Muhammad Usman, et al.
Publicado: (2019)

Genetic analysis of ACE2 peptidase domain in SARS-CoV-2-positive and SARS-CoV-2-negative individuals from Pakistan
por: Muhammad, Noor, et al.
Publicado: (2023)

Comparison of BRCA versus non-BRCA germline mutations and associated somatic mutation profiles in patients with unselected breast cancer
por: Chen, Bo, et al.
Publicado: (2020)

Prevalence of tumor BRCA1 and BRCA2 dysfunction in unselected patients with ovarian cancer
por: Kalachand, Roshni D., et al.
Publicado: (2020)

Predominance of BRCA2 Mutation and Estrogen Receptor Positivity in Unselected Breast Cancer with BRCA1 or BRCA2 Mutation
por: Pujol, Pascal, et al.
Publicado: (2022)

National External Quality Assurance Program Pakistan (NEQAPP) –A Milestone in Proficiency Testing in Pakistan
por: Munir, Muhammad Usman, et al.
Publicado: (2016)

Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Greece
por: Koumpis, Chrissovaladis, et al.
Publicado: (2011)

The frequency of the predominant Jewish mutations in BRCA1 and BRCA2 in unselected Ashkenazi colorectal cancer patients
por: Chen-Shtoyerman, R, et al.
Publicado: (2001)

Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from medellín, Colombia
por: Hernández, Julián Esteban Londoño, et al.
Publicado: (2014)

Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
por: Li, Jingmei, et al.
Publicado: (2018)

High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2016)

Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2020)

BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers
por: Maxwell, Kara N., et al.
Publicado: (2017)

Correction to: Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2021)

The germline mutational landscape of BRCA1 and BRCA2 in Brazil
por: Palmero, Edenir Inêz, et al.
Publicado: (2018)

BRCA1 and BRCA2 germline mutation analysis in the Indonesian population
por: Purnomosari, Dewajani, et al.
Publicado: (2007)

Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort
por: Liu, Yun, et al.
Publicado: (2021)

The occurrence of germline BRCA1 and BRCA2 sequence alterations in Slovenian population
por: Stegel, Vida, et al.
Publicado: (2011)

BRCAsearch: written pre-test information and BRCA1/2 germline mutation testing in unselected patients with newly diagnosed breast cancer
por: Nilsson, Martin P., et al.
Publicado: (2017)

Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia
por: Wen, Wei Xiong, et al.
Publicado: (2018)

Contribution of BRCA1 and BRCA2 Germline Mutations to Early Algerian Breast Cancer
por: Henouda, Sarra, et al.
Publicado: (2016)

Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil
por: Maistro, Simone, et al.
Publicado: (2016)

BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
por: Vos, Shoko, et al.
Publicado: (2017)

Melanoma predisposition—A limited role for germline BRCA1 and BRCA2 variants
por: Adams, David J., et al.
Publicado: (2019)

Germline BRCA1 and BRCA2 mutations and the risk of bladder or kidney cancer in Poland
por: Złowocka-Perłowska, Elżbieta, et al.
Publicado: (2022)

Landscape of germline BRCA1/BRCA2 variants in breast and ovarian cancer in Peru
por: Ferreyra, Yomali, et al.
Publicado: (2023)

A novel deleterious c.2656G>T MSH2 germline mutation in a Pakistani family with a phenotypic overlap of hereditary breast and ovarian cancer and Lynch syndrome
por: Rashid, Muhammad U., et al.
Publicado: (2016)

Evaluation of models to predict BRCA germline mutations
por: Kang, H H, et al.
Publicado: (2006)

Targeted sequencing of BRCA1 and BRCA2 across a large unselected breast cancer cohort suggests that one-third of mutations are somatic
por: Winter, C., et al.
Publicado: (2016)

Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2
por: Ligtenberg, M J L, et al.
Publicado: (1999)

Nipple aspiration and ductal lavage in women with a germline BRCA1 or BRCA2 mutation
por: Mitchell, Gillian, et al.
Publicado: (2005)

Contribution of germline BRCA1 and BRCA2 sequence alterations to breast cancer in Northern India
por: Saxena, Sunita, et al.
Publicado: (2006)

PARP inhibitors in BRCA1/BRCA2 germline mutation carriers with ovarian and breast cancer
por: Annunziata, Christina M, et al.
Publicado: (2010)

BRCA1 and BRCA2 Germline Mutations Screening in Algerian Breast/Ovarian Cancer Families
por: Cherbal, Farid, et al.
Publicado: (2010)

Germline Mutations in BRCA1 and BRCA2 in Polish Families Predisposed to Breast and Ovary Cancers
por: Grzybowska, E., et al.
Publicado: (1999)

Anti-Müllerian hormone serum concentrations of women with germline BRCA1 or BRCA2 mutations
por: Phillips, Kelly-Anne, et al.
Publicado: (2016)

Prevalence and Penetrance of BRCA1 and BRCA2 Germline Mutations in Colombian Breast Cancer Patients
por: Torres, D., et al.
Publicado: (2017)

Novel Germline Mutations of BRCA1 and BRCA2 in Korean Familial Breast Cancer Patients
por: Kim, Hee Nam, et al.
Publicado: (2019)

Management Strategies of Breast Cancer Patients with BRCA1 and BRCA2 Pathogenic Germline Variants
por: Edaily, Sarah, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_52ed3lt45gkehao3kgrnlqv3i7