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Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential
Mitochondrial dysfunction is strongly implicated in the etiology of idiopathic and genetic Parkinson’s disease (PD). However, strategies aimed at ameliorating mitochondrial dysfunction, including antioxidants, antidiabetic drugs, and iron chelators, have failed in disease-modification clinical trial...
Autores principales: | Henrich, Martin T., Oertel, Wolfgang H., Surmeier, D. James, Geibl, Fanni F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640762/ https://www.ncbi.nlm.nih.gov/pubmed/37951933 http://dx.doi.org/10.1186/s13024-023-00676-7 |
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