Clinical Antiviral Efficacy of Remdesivir in Coronavirus Disease 2019: An Open-Label, Randomized Controlled Adaptive Platform Trial (PLATCOV)

BACKGROUND: Uncertainty over the therapeutic benefit of parenteral remdesivir in coronavirus disease 2019 (COVID-19) has resulted in varying treatment guidelines. METHODS: In a multicenter open-label, controlled, adaptive, pharmacometric platform trial, low-risk adult patients with early symptomatic...

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Detalles Bibliográficos
Autores principales: Jittamala, Podjanee, Schilling, William H K, Watson, James A, Luvira, Viravarn, Siripoon, Tanaya, Ngamprasertchai, Thundon, Almeida, Pedro J, Ekkapongpisit, Maneerat, Cruz, Cintia, Callery, James J, Boyd, Simon, Anunsittichai, Orawan, Hongsuwan, Maliwan, Singhaboot, Yutatirat, Pagornrat, Watcharee, Tuntipaiboontana, Runch, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tubprasert, Jaruwan, Abdad, Mohammad Yazid, Keayarsa, Srisuda, Madmanee, Wanassanan, Aguiar, Renato S, Santos, Franciele M, Batty, Elizabeth M, Hanboonkunupakarn, Pongtorn, Hanboonkunupakarn, Borimas, Sookprome, Sakol, Poovorawan, Kittiyod, Imwong, Mallika, Taylor, Walter R J, Chotivanich, Vasin, Sangketchon, Chunlanee, Ruksakul, Wiroj, Chotivanich, Kesinee, Pukrittayakamee, Sasithon, Dondorp, Arjen M, Day, Nicholas P J, Teixeira, Mauro M, Piyaphanee, Watcharapong, Phumratanaprapin, Weerapong, White, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640773/
https://www.ncbi.nlm.nih.gov/pubmed/37470445
http://dx.doi.org/10.1093/infdis/jiad275

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