Cargando…
GW4869 Can Inhibit Epithelial-Mesenchymal Transition and Extracellular HSP90α in Gefitinib-Sensitive NSCLC Cells
OBJECTIVE: GW4869 is an exosomal inhibitor. It is necessary to delay the occurrence of gefitinib resistance during non-small-cell lung cancer (NSCLC) treatment. This study aimed to investigate the anti-tumor effects of GW4869 on epithelial-mesenchymal transition (EMT) and expression of extracellular...
Autores principales: | Wan, Xuan, Fang, Yuting, Du, Jiangzhou, Cai, Shaoxi, Dong, Hangming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640835/ https://www.ncbi.nlm.nih.gov/pubmed/38021444 http://dx.doi.org/10.2147/OTT.S428707 |
Ejemplares similares
-
Epithelial-to-mesenchymal transition correlates with gefitinib resistance in NSCLC cells and the liver X receptor ligand GW3965 reverses gefitinib resistance through inhibition of vimentin
por: Hu, Yong, et al.
Publicado: (2017) -
Blockade of exosome generation by GW4869 inhibits the education of M2 macrophages in prostate cancer
por: Peng, Yilin, et al.
Publicado: (2022) -
The Promotional Effect of GW4869 on C. albicans Invasion and Cellular Damage in a Murine Model of Oral Candidiasis
por: Zhang, Miaomiao, et al.
Publicado: (2022) -
The role of secreted Hsp90α in HDM-induced asthmatic airway epithelial barrier dysfunction
por: Ye, Cuiping, et al.
Publicado: (2019) -
Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869
por: Huang, Yunlong, et al.
Publicado: (2018)