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LPA(2) Alleviates Septic Acute Lung Injury via Protective Endothelial Barrier Function Through Activation of PLC-PKC-FAK
BACKGROUND: Increased endothelial permeability of pulmonary vessels is a primary pathological characteristic of septic acute lung injury (ALI). Previously, elevated lysophosphatidic acid (LPA) levels and LPA(2) (an LPA receptor) expression have been found in the peripheral blood and lungs of septic...
Autores principales: | Bai, Ruifeng, Pei, Jianqiu, Pei, Shengqiang, Cong, Xiangfeng, Chun, Jerold, Wang, Fang, Chen, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640838/ https://www.ncbi.nlm.nih.gov/pubmed/38026263 http://dx.doi.org/10.2147/JIR.S419578 |
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