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LPA(2) Alleviates Septic Acute Lung Injury via Protective Endothelial Barrier Function Through Activation of PLC-PKC-FAK

BACKGROUND: Increased endothelial permeability of pulmonary vessels is a primary pathological characteristic of septic acute lung injury (ALI). Previously, elevated lysophosphatidic acid (LPA) levels and LPA(2) (an LPA receptor) expression have been found in the peripheral blood and lungs of septic...

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Detalles Bibliográficos
Autores principales: Bai, Ruifeng, Pei, Jianqiu, Pei, Shengqiang, Cong, Xiangfeng, Chun, Jerold, Wang, Fang, Chen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640838/
https://www.ncbi.nlm.nih.gov/pubmed/38026263
http://dx.doi.org/10.2147/JIR.S419578

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