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Stanniocalcin 1a regulates organismal calcium balance and survival by suppressing Trpv6 expression and inhibiting IGF signaling in zebrafish

Stanniocalcin 1 (Stc1) is well known for its role in regulating calcium uptake in fish by acting on ionocytes or NaR cells. A hallmark of NaR cells is the expression of Trpv6, a constitutively open calcium channel. Recent studies in zebrafish suggest that genetical deletion of Stc1a and Trpv6 indivi...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Li, Helena, Wang, Zhengyi, Duan, Cunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640984/
https://www.ncbi.nlm.nih.gov/pubmed/37964974
http://dx.doi.org/10.3389/fendo.2023.1276348