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The role of laboratory investigations in the classification of tremors

INTRODUCTION: Tremor is the most common movement disorder. Although clinical examination plays a significant role in evaluating patients with tremor, laboratory tests are useful to classify tremors according to the recent two-axis approach proposed by the International Parkinson and Movement Disorde...

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Autores principales: Angelini, Luca, Terranova, Roberta, Lazzeri, Giulia, van den Berg, Kevin R E, Dirkx, Michiel F, Paparella, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641063/
https://www.ncbi.nlm.nih.gov/pubmed/37814130
http://dx.doi.org/10.1007/s10072-023-07108-w
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author Angelini, Luca
Terranova, Roberta
Lazzeri, Giulia
van den Berg, Kevin R E
Dirkx, Michiel F
Paparella, Giulia
author_facet Angelini, Luca
Terranova, Roberta
Lazzeri, Giulia
van den Berg, Kevin R E
Dirkx, Michiel F
Paparella, Giulia
author_sort Angelini, Luca
collection PubMed
description INTRODUCTION: Tremor is the most common movement disorder. Although clinical examination plays a significant role in evaluating patients with tremor, laboratory tests are useful to classify tremors according to the recent two-axis approach proposed by the International Parkinson and Movement Disorders Society. METHODS: In the present review, we will discuss the usefulness and applicability of the various diagnostic methods in classifying and diagnosing tremors. We will evaluate a number of techniques, including laboratory and genetic tests, neurophysiology, and neuroimaging. The role of newly introduced innovative tremor assessment methods will also be discussed. RESULTS: Neurophysiology plays a crucial role in tremor definition and classification, and it can be useful for the identification of specific tremor syndromes. Laboratory and genetic tests and neuroimaging may be of paramount importance in identifying specific etiologies. Highly promising innovative technologies are being developed for both clinical and research purposes. CONCLUSIONS: Overall, laboratory investigations may support clinicians in the diagnostic process of tremor. Also, combining data from different techniques can help improve understanding of the pathophysiological bases underlying tremors and guide therapeutic management.
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spelling pubmed-106410632023-11-14 The role of laboratory investigations in the classification of tremors Angelini, Luca Terranova, Roberta Lazzeri, Giulia van den Berg, Kevin R E Dirkx, Michiel F Paparella, Giulia Neurol Sci Review Article INTRODUCTION: Tremor is the most common movement disorder. Although clinical examination plays a significant role in evaluating patients with tremor, laboratory tests are useful to classify tremors according to the recent two-axis approach proposed by the International Parkinson and Movement Disorders Society. METHODS: In the present review, we will discuss the usefulness and applicability of the various diagnostic methods in classifying and diagnosing tremors. We will evaluate a number of techniques, including laboratory and genetic tests, neurophysiology, and neuroimaging. The role of newly introduced innovative tremor assessment methods will also be discussed. RESULTS: Neurophysiology plays a crucial role in tremor definition and classification, and it can be useful for the identification of specific tremor syndromes. Laboratory and genetic tests and neuroimaging may be of paramount importance in identifying specific etiologies. Highly promising innovative technologies are being developed for both clinical and research purposes. CONCLUSIONS: Overall, laboratory investigations may support clinicians in the diagnostic process of tremor. Also, combining data from different techniques can help improve understanding of the pathophysiological bases underlying tremors and guide therapeutic management. Springer International Publishing 2023-10-10 2023 /pmc/articles/PMC10641063/ /pubmed/37814130 http://dx.doi.org/10.1007/s10072-023-07108-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Angelini, Luca
Terranova, Roberta
Lazzeri, Giulia
van den Berg, Kevin R E
Dirkx, Michiel F
Paparella, Giulia
The role of laboratory investigations in the classification of tremors
title The role of laboratory investigations in the classification of tremors
title_full The role of laboratory investigations in the classification of tremors
title_fullStr The role of laboratory investigations in the classification of tremors
title_full_unstemmed The role of laboratory investigations in the classification of tremors
title_short The role of laboratory investigations in the classification of tremors
title_sort role of laboratory investigations in the classification of tremors
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641063/
https://www.ncbi.nlm.nih.gov/pubmed/37814130
http://dx.doi.org/10.1007/s10072-023-07108-w
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