Polyurethane scaffold-based 3D lung cancer model recapitulates in vivo tumor biological behavior for nanoparticulate drug screening

Lung cancer is the leading cause of cancer mortality worldwide. Preclinical studies in lung cancer hold the promise of screening for effective antitumor agents, but mechanistic studies and drug discovery based on 2D cell models have a high failure rate in getting to the clinic. Thus, there is an urg...

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Detalles Bibliográficos
Autores principales: Sun, Lu, Wang, Xiaofei, He, Yushui, Chen, Boran, Shan, Baoyin, Yang, Jinlong, Wang, Ruoran, Zeng, Xihang, Li, Jiehua, Tan, Hong, Liang, Ruichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641150/
https://www.ncbi.nlm.nih.gov/pubmed/37965109
http://dx.doi.org/10.1093/rb/rbad091

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