8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-κB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276

Nuclear factor kappa B (NF-κB) activity is regulated by various posttranslational modifications, of which Ser276 phosphorylation of RelA/p65 is particularly impacted by reactive oxygen species (ROS). This modification is responsible for selective upregulation of a subset of NF-κB targets; however, t...

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Detalles Bibliográficos
Autores principales: Xue, Yaoyao, Li, Chunshuang, Deng, Shihua, Chen, Xin, Han, Jinling, Zheng, Xu, Tian, Miaomiao, Hao, Wenjing, Pan, Lang, Boldogh, Istvan, Ba, Xueqing, Wang, Ruoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641171/
https://www.ncbi.nlm.nih.gov/pubmed/37778730
http://dx.doi.org/10.1016/j.jbc.2023.105308

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