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Exploring disease-causing traits for drug repurposing in critically ill COVID-19 patients: A causal inference approach

Despite recent development of vaccines to prevent SARS-CoV-2 infection, treatment of critically ill COVID-19 patients remains an important goal. In principle, genome-wide association studies (GWASs) provide a shortcut to the clinical evidence needed to repurpose existing drugs; however, genes identi...

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Detalles Bibliográficos
Autores principales: Baukmann, Hannes A., Cope, Justin L., Bannard, Colin, Schwinges, Alexander R.E.C., Lamparter, Margaretha R.J., Groves, Sarah, Ravarani, Charles N.J., Amulic, Borko, Klinger, Joern E., Schmidt, Marco F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641251/
https://www.ncbi.nlm.nih.gov/pubmed/37965141
http://dx.doi.org/10.1016/j.isci.2023.108185