Outer membrane protein 25 of Brucella suppresses TLR-mediated expression of proinflammatory cytokines through degradation of TLRs and adaptor proteins

Toll-like receptors (TLRs) are essential components of innate immunity that serves as the first line of defense against the invaded microorganisms. However, successful infectious pathogens subvert TLR signaling to suppress the activation of innate and adaptive responses. Brucella species are infecti...

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Detalles Bibliográficos
Autores principales: Murugan, Subathra, Nandi, Binita Roy, Mazumdar, Varadendra, Joshi, Kiranmai, Nandini, Prachita, Namani, Swapna, Jakka, Padmaja, Radhakrishnan, Girish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641269/
https://www.ncbi.nlm.nih.gov/pubmed/37778729
http://dx.doi.org/10.1016/j.jbc.2023.105309

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