The structure of NAD(+) consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations

Toll-like and interleukin-1/18 receptor/resistance (TIR) domain–containing proteins function as important signaling and immune regulatory molecules. TIR domain–containing proteins identified in eukaryotic and prokaryotic species also exhibit NAD+ hydrolase activity in select bacteria, plants, and ma...

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Detalles Bibliográficos
Autores principales: Klontz, Erik, Obi, Juliet O., Wang, Yajing, Glendening, Gabrielle, Carr, Jahid, Tsibouris, Constantine, Buddula, Sahthi, Nallar, Shreeram, Soares, Alexei S., Beckett, Dorothy, Redzic, Jasmina S., Eisenmesser, Elan, Palm, Cheyenne, Schmidt, Katrina, Scudder, Alexis H., Obiorah, Trinity, Essuman, Kow, Milbrandt, Jeffrey, Diantonio, Aaron, Ray, Krishanu, Snyder, Michelle L.D., Deredge, Daniel, Snyder, Greg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641520/
https://www.ncbi.nlm.nih.gov/pubmed/37758001
http://dx.doi.org/10.1016/j.jbc.2023.105290

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