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Ancient duplication, coevolution, and selection at the MHC class IIA and IIB genes of birds

INTRODUCTION: The Major Histocompatibility Complex (MHC) of vertebrates is a dynamically evolving multigene family primarily responsible for recognizing non-self peptide antigens and triggering a pathogen-specific adaptive immune response. In birds, the MHC was previously thought to evolve via conce...

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Detalles Bibliográficos
Autores principales: Minias, Piotr, Edwards, Scott V., Babik, Wiesław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641522/
https://www.ncbi.nlm.nih.gov/pubmed/37965325
http://dx.doi.org/10.3389/fimmu.2023.1250824