A conserved, noncanonical insert in FIS1 mediates TBC1D15 and DRP1 recruitment for mitochondrial fission

Mitochondrial fission protein 1 (FIS1) is conserved in all eukaryotes, yet its function in metazoans is thought divergent. Structure-based sequence alignments of FIS1 revealed a conserved, but noncanonical, three-residue insert in its first tetratricopeptide repeat (TPR) suggesting a conserved funct...

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Detalles Bibliográficos
Autores principales: Ihenacho, Ugochukwu K., Toro, Rafael, Mansour, Rana H., Hill, R. Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641528/
https://www.ncbi.nlm.nih.gov/pubmed/37777154
http://dx.doi.org/10.1016/j.jbc.2023.105303

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