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Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients

Autoantibodies to malondialdehyde (MDA) proteins constitute a subset of anti-modified protein autoantibodies in rheumatoid arthritis (RA), which is distinct from citrulline reactivity. Serum anti-MDA IgG levels are commonly elevated in RA and correlate with disease activity, CRP, IL6, and TNF-α. MDA...

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Detalles Bibliográficos
Autores principales:	Sahlström, Peter, Joshua, Vijay, Valkovskaia, Viktoriia, Biese, Charlotte, Stålesen, Ragnhild, Israelsson, Lena, Végvári, Ákos, Scheel-Toellner, Dagmar, Klareskog, Lars, Hansson, Monika, Hensvold, Aase, Malmström, Vivianne, Grönwall, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641667/ https://www.ncbi.nlm.nih.gov/pubmed/37802315 http://dx.doi.org/10.1016/j.jbc.2023.105320

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