Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc

INTRODUCTION: T cell expressed CD27 provides costimulation upon binding to inducible membrane expressed trimeric CD70 and is required for protective CD8 T cell responses. CD27 agonists could therefore be used to bolster cellular vaccines and anti-tumour immune responses. To date, clinical developmen...

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Detalles Bibliográficos
Autores principales: Dadas, Osman, Allen, Joel D., Buchan, Sarah L., Kim, Jinny, Chan, H. T. Claude, Mockridge, C. Ian, Duriez, Patrick J., Rogel, Anne, Crispin, Max, Al-Shamkhani, Aymen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641686/
https://www.ncbi.nlm.nih.gov/pubmed/37965342
http://dx.doi.org/10.3389/fimmu.2023.1252274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641686/
https://www.ncbi.nlm.nih.gov/pubmed/37965342
http://dx.doi.org/10.3389/fimmu.2023.1252274

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