Noninvasive diagnosis of secondary infections in COVID-19 by sequencing of plasma microbial cell-free DNA

Secondary infection (SI) diagnosis in severe COVID-19 remains challenging. We correlated metagenomic sequencing of plasma microbial cell-free DNA (mcfDNA-Seq) with clinical SI assessment, immune response, and outcomes. We classified 42 COVID-19 inpatients as microbiologically confirmed-SI (Micro-SI,...

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Detalles Bibliográficos
Autores principales: Lisius, Grace, Duttagupta, Radha, Ahmed, Asim A., Hensley, Matthew, Al-Yousif, Nameer, Lu, Michael, Bain, William, Shah, Faraaz, Blauwkamp, Timothy A., Bercovici, Sivan, Schaefer, Caitlin, Qin, Shulin, Wang, Xiaohong, Zhang, Yingze, Mitchell, Kevin J., Hughes, Ellen K., Jacobs, Jana L., Naqvi, Asma, Haidar, Ghady, Mellors, John W., Methé, Barbara, McVerry, Bryan J., Morris, Alison, Kitsios, Georgios D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641743/
https://www.ncbi.nlm.nih.gov/pubmed/37965142
http://dx.doi.org/10.1016/j.isci.2023.108093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641743/
https://www.ncbi.nlm.nih.gov/pubmed/37965142
http://dx.doi.org/10.1016/j.isci.2023.108093

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