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Blockade of IL-18Rα-mediated signaling pathway exacerbates neutrophil infiltration in imiquimod-induced psoriasis murine model

Psoriasis is an immune-mediated inflammatory disease of the skin, which is characterized by epidermal hyperkeratosis and neutrophil infiltration. The interleukin (IL)-17/IL-23 pathway and associated cytokines play major roles in the pathogenesis and exacerbation of psoriasis. The IL-18/IL-18 recepto...

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Detalles Bibliográficos
Autores principales:	Akazawa, Hiroki, Nozaki, Yuji, Yamazawa, Hirotaka, Ishimura, Kaori, Ashida, Chisato, Okada, Akinori, Kinoshita, Koji, Matsumura, Itaru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641785/ https://www.ncbi.nlm.nih.gov/pubmed/37964882 http://dx.doi.org/10.3389/fmed.2023.1293132

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