Fused Tetrahydroquinolines Are Interfering with Your Assay

[Image: see text] Tricyclic tetrahydroquinolines (THQs) have been repeatedly reported as hits across a diverse range of high-throughput screening (HTS) campaigns. The activities of these compounds, however, are likely due to reactive byproducts that interfere with the assay. As a lesser studied clas...

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Detalles Bibliográficos
Autores principales: Bashore, Frances M., Annor-Gyamfi, Joel, Du, Yuhong, Katis, Vittorio, Nwogbo, Felix, Flax, Raymond G., Frye, Stephen V., Pearce, Kenneth H., Fu, Haian, Willson, Timothy M., Drewry, David H., Axtman, Alison D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641811/
https://www.ncbi.nlm.nih.gov/pubmed/37874947
http://dx.doi.org/10.1021/acs.jmedchem.3c01277

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