The autism spectrum disorder risk gene NEXMIF over-synchronizes hippocampal CA1 network and alters neuronal coding

Mutations in autism spectrum disorder (ASD) risk genes disrupt neural network dynamics that ultimately lead to abnormal behavior. To understand how ASD-risk genes influence neural circuit computation during behavior, we analyzed the hippocampal network by performing large-scale cellular calcium imag...

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Detalles Bibliográficos
Autores principales: Mount, Rebecca A., Athif, Mohamed, O’Connor, Margaret, Saligrama, Amith, Tseng, Hua-an, Sridhar, Sudiksha, Zhou, Chengqian, Bortz, Emma, San Antonio, Erynne, Kramer, Mark A., Man, Heng-Ye, Han, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641898/
https://www.ncbi.nlm.nih.gov/pubmed/37965217
http://dx.doi.org/10.3389/fnins.2023.1277501

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