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Efficacy, safety, and pharmacokinetics of MR13A11A, a generic of remifentanil, for pain management of Japanese patients in the intensive care unit: a double-blinded, fentanyl-controlled, randomized, non-inferiority phase 3 study

BACKGROUND: The aims of this study were to evaluate the efficacy, safety, and pharmacokinetics (PK) of continuous intravenous administration of remifentanil in mechanically ventilated patients in the intensive care unit (ICU). METHODS: This was a multicenter, randomized, double-blinded, fentanyl-con...

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Detalles Bibliográficos
Autores principales: Doi, Matsuyuki, Takahashi, Naoki, Nojiri, Rumi, Hiraoka, Takehiko, Kishimoto, Yusuke, Inoue, Shinichi, Oya, Nobuyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641973/
https://www.ncbi.nlm.nih.gov/pubmed/37953283
http://dx.doi.org/10.1186/s40560-023-00698-9