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Efficacy, safety, and pharmacokinetics of MR13A11A, a generic of remifentanil, for pain management of Japanese patients in the intensive care unit: a double-blinded, fentanyl-controlled, randomized, non-inferiority phase 3 study
BACKGROUND: The aims of this study were to evaluate the efficacy, safety, and pharmacokinetics (PK) of continuous intravenous administration of remifentanil in mechanically ventilated patients in the intensive care unit (ICU). METHODS: This was a multicenter, randomized, double-blinded, fentanyl-con...
Autores principales: | Doi, Matsuyuki, Takahashi, Naoki, Nojiri, Rumi, Hiraoka, Takehiko, Kishimoto, Yusuke, Inoue, Shinichi, Oya, Nobuyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641973/ https://www.ncbi.nlm.nih.gov/pubmed/37953283 http://dx.doi.org/10.1186/s40560-023-00698-9 |
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