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Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis
The limited sensitivity of circulating tumor cell (CTC) detection in pancreatic adenocarcinoma (PDAC) stems from their extremely low concentration in the whole circulating blood, necessitating enhanced detection methodologies. This study sought to amplify assay-sensitivity by employing diagnostic le...
Autores principales: | Stoecklein, Nikolas H., Fluegen, Georg, Guglielmi, Rosa, Neves, Rui P.L., Hackert, Thilo, Birgin, Emrullah, Cieslik, Stefan A., Sudarsanam, Monica, Driemel, Christiane, van Dalum, Guus, Franken, André, Niederacher, Dieter, Neubauer, Hans, Fehm, Tanja, Rox, Jutta M., Böhme, Petra, Häberle, Lena, Göring, Wolfgang, Esposito, Irene, Topp, Stefan A., Coumans, Frank A.W., Weitz, Jürgen, Knoefel, Wolfram T., Fischer, Johannes C., Bork, Ulrich, Rahbari, Nuh N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641981/ https://www.ncbi.nlm.nih.gov/pubmed/37957606 http://dx.doi.org/10.1186/s12943-023-01880-1 |
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