Borealin/CDCA8 deficiency alters thyroid development and results in papillary tumor-like structures

BACKGROUND: BOREALIN/CDCA8 mutations are associated with congenital hypothyroidism and thyroid dysgenesis. Borealin is involved in mitosis as part of the Chromosomal Passenger Complex. Although BOREALIN mutations decrease thyrocyte adhesion and migration, little is known about the specific role of B...

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Detalles Bibliográficos
Autores principales: Didier-Mathon, Hortense, Stoupa, Athanasia, Kariyawasam, Dulanjalee, Yde, Sonny, Cochant-Priollet, Beatrix, Groussin, Lionel, Sébag, Frédéric, Cagnard, Nicolas, Nitschke, Patrick, Luton, Dominique, Polak, Michel, Carré, Aurore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641986/
https://www.ncbi.nlm.nih.gov/pubmed/37964961
http://dx.doi.org/10.3389/fendo.2023.1286747

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