Cargando…

Integrative transcriptomic and network pharmacology analysis reveals the neuroprotective role of BYHWD through enhancing autophagy by inhibiting Ctsb in intracerebral hemorrhage mice

BACKGROUND: In this study, we aimed to combine transcriptomic and network pharmacology to explore the crucial mRNAs and specific regulatory molecules of Buyang Huanwu Decoction (BYHWD) in intracerebral hemorrhage (ICH) treatment. METHODS: C57BL/6 mice were randomly divided into three groups: sham, I...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Yiqing, Yu, Zhe, Yang, Xueping, Luo, Weikang, Hu, En, Li, Teng, Zhu, Wenxin, Wang, Yang, Tang, Tao, Luo, Jiekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642062/
https://www.ncbi.nlm.nih.gov/pubmed/37957754
http://dx.doi.org/10.1186/s13020-023-00852-3