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SQSTM1/p62 and Hepatic Mallory-Denk Body Formation in Alcohol-Associated Liver Disease

Sequestosome 1 (SQSTM1/p62; hereafter p62) is an autophagy receptor protein for selective autophagy primarily due to its direct interaction with the microtubule light chain 3 protein that specifically localizes on autophagosome membranes. As a result, impaired autophagy leads to the accumulation of...

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Detalles Bibliográficos
Autores principales: Qian, Hui, Ding, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642158/
https://www.ncbi.nlm.nih.gov/pubmed/36906265
http://dx.doi.org/10.1016/j.ajpath.2023.02.015