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Development and validation of an LC–MS/MS method for the simultaneous quantification of milbemycin oxime and praziquantel in plasma: application to a pharmacokinetic study in cats

INTRODUCTION: Milbemycin oxime (MBO) and praziquantel (PZQ) have a broad spectrum of biological activity and are commonly used to treat the parasitic infection in the veterinary clinic. In this study, a fast and efficient LC-MS/MS method was established and validated for the simultaneous determinati...

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Detalles Bibliográficos
Autores principales: Xie, Shiting, Lu, Yixing, Wang, Jun, Lin, Changcheng, Ye, Peiyu, Liu, Xiaolin, Xiong, Wenguang, Zeng, Zhenling, Zeng, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642303/
https://www.ncbi.nlm.nih.gov/pubmed/37964913
http://dx.doi.org/10.3389/fvets.2023.1285932