Mechanopathology of biofilm-like Mycobacterium tuberculosis cords

Mycobacterium tuberculosis (Mtb) cultured axenically without detergent forms biofilm-like cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in alveolar cells contribute to suppression of innate immune signaling via nuclear compression. Thereafter, extracellular...

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Detalles Bibliográficos
Autores principales: Mishra, Richa, Hannebelle, Melanie, Patil, Vishal P., Dubois, Anaëlle, Garcia-Mouton, Cristina, Kirsch, Gabriela M., Jan, Maxime, Sharma, Kunal, Guex, Nicolas, Sordet-Dessimoz, Jessica, Perez-Gil, Jesus, Prakash, Manu, Knott, Graham W., Dhar, Neeraj, McKinney, John D., Thacker, Vivek V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642369/
https://www.ncbi.nlm.nih.gov/pubmed/37865090
http://dx.doi.org/10.1016/j.cell.2023.09.016

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