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Effects of thrombopoietin pre-treatment on peri-liver transplantation thrombocytopenia in a mouse model of cirrhosis with hypersplenism

BACKGROUND: During cirrhosis, the liver is impaired and unable to synthesize and clear thrombopoietin properly. At the same time, the spleen assumes the function of hemofiltration and storage due to liver dysfunction, resulting in hypersplenism and excessive removal of platelets in the spleen, furth...

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Detalles Bibliográficos
Autores principales: Liu, Zi-Rong, Zhang, Ya-Min, Cui, Zi-Lin, Tong, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642473/
https://www.ncbi.nlm.nih.gov/pubmed/37969704
http://dx.doi.org/10.4240/wjgs.v15.i10.2115

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