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Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams
PURPOSE: The purpose of the study was to investigate the dosimetric characteristics of radiophotoluminescent glass dosimeters (RGDs) for pencil beam scanning proton therapy. The RGD’s end-to-end testing of intensity-modulated proton therapy (IMPT) plans was also evaluated. MATERIALS AND METHODS: The...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642601/ https://www.ncbi.nlm.nih.gov/pubmed/37969142 http://dx.doi.org/10.4103/jmp.jmp_71_23 |
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author | Oonsiri, Sornjarod Kingkaew, Sakda Vimolnoch, Mananchaya Chatchumnan, Nichakan Oonsiri, Puntiwa |
author_facet | Oonsiri, Sornjarod Kingkaew, Sakda Vimolnoch, Mananchaya Chatchumnan, Nichakan Oonsiri, Puntiwa |
author_sort | Oonsiri, Sornjarod |
collection | PubMed |
description | PURPOSE: The purpose of the study was to investigate the dosimetric characteristics of radiophotoluminescent glass dosimeters (RGDs) for pencil beam scanning proton therapy. The RGD’s end-to-end testing of intensity-modulated proton therapy (IMPT) plans was also evaluated. MATERIALS AND METHODS: The dosimetric characteristics of the GD-302M type glass dosimeter were studied in terms of uniformity, short-term and long-term reproducibility, stability of the magazine position readout, dose linearity in the range from 0.2 to 20 Gy, energy response in 70–220 MeV, and fading effect. The reference conditions of the spot scanning beam from the Varian ProBeam Compact system were operation at 160 MeV, a 2 cm water-equivalent depth in a solid water phantom, a 10 cm × 10 cm field size at the isocenter, and 2 Gy dose delivery. End-to-end testing of IMPT plans for the head, abdomen, and pelvis was verified using the Alderson Rando phantom. The overall uncertainty analysis was confirmed in this study. RESULTS: The relative response of RGDs for the uniformity test was within 0.95–1.05. The percentages of the coefficients of variation for short-term and long-term reproducibility were 1.16% and 1.50%, respectively. The dose ACE glass dosimetry reader FGD-1000 showed a stable magazine position readout. The dose was found to be linear with R(2) = 0.9988. The energy response relative to 160 MeV was approximately within 4.0%. The fading effect was within 2.4%. For the end-to-end test, the difference between the treatment plan and RGD measurement was within 1.0%. The overall uncertainty of the RGD measurement for the proton beam was 4.6%, which covered all energy ranges in this study. CONCLUSION: The experimental study indicates that the RGDs have the potential to be used in the dosimetry of therapeutic proton beams, including end-to-end dosimetry. |
format | Online Article Text |
id | pubmed-10642601 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-106426012023-11-15 Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams Oonsiri, Sornjarod Kingkaew, Sakda Vimolnoch, Mananchaya Chatchumnan, Nichakan Oonsiri, Puntiwa J Med Phys Original Article PURPOSE: The purpose of the study was to investigate the dosimetric characteristics of radiophotoluminescent glass dosimeters (RGDs) for pencil beam scanning proton therapy. The RGD’s end-to-end testing of intensity-modulated proton therapy (IMPT) plans was also evaluated. MATERIALS AND METHODS: The dosimetric characteristics of the GD-302M type glass dosimeter were studied in terms of uniformity, short-term and long-term reproducibility, stability of the magazine position readout, dose linearity in the range from 0.2 to 20 Gy, energy response in 70–220 MeV, and fading effect. The reference conditions of the spot scanning beam from the Varian ProBeam Compact system were operation at 160 MeV, a 2 cm water-equivalent depth in a solid water phantom, a 10 cm × 10 cm field size at the isocenter, and 2 Gy dose delivery. End-to-end testing of IMPT plans for the head, abdomen, and pelvis was verified using the Alderson Rando phantom. The overall uncertainty analysis was confirmed in this study. RESULTS: The relative response of RGDs for the uniformity test was within 0.95–1.05. The percentages of the coefficients of variation for short-term and long-term reproducibility were 1.16% and 1.50%, respectively. The dose ACE glass dosimetry reader FGD-1000 showed a stable magazine position readout. The dose was found to be linear with R(2) = 0.9988. The energy response relative to 160 MeV was approximately within 4.0%. The fading effect was within 2.4%. For the end-to-end test, the difference between the treatment plan and RGD measurement was within 1.0%. The overall uncertainty of the RGD measurement for the proton beam was 4.6%, which covered all energy ranges in this study. CONCLUSION: The experimental study indicates that the RGDs have the potential to be used in the dosimetry of therapeutic proton beams, including end-to-end dosimetry. Wolters Kluwer - Medknow 2023 2023-09-18 /pmc/articles/PMC10642601/ /pubmed/37969142 http://dx.doi.org/10.4103/jmp.jmp_71_23 Text en Copyright: © 2023 Journal of Medical Physics https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Oonsiri, Sornjarod Kingkaew, Sakda Vimolnoch, Mananchaya Chatchumnan, Nichakan Oonsiri, Puntiwa Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams |
title | Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams |
title_full | Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams |
title_fullStr | Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams |
title_full_unstemmed | Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams |
title_short | Dosimetric Characteristics of Radiophotoluminescent Glass Dosimeters for Proton Beams |
title_sort | dosimetric characteristics of radiophotoluminescent glass dosimeters for proton beams |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642601/ https://www.ncbi.nlm.nih.gov/pubmed/37969142 http://dx.doi.org/10.4103/jmp.jmp_71_23 |
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